Techniques for Developing Raw Material Libraries

For many years, pharmaceutical and related industries have used near-infrared spectroscopy
(NIRS) as a means to identify raw materials as they are received by a manufacturing facility.
The NIRS technique is highly specific for many of the organic compounds used in the
formulation of tablets, capsules, crèmes, and suspensions.
The development of portable and smaller instrumentation has helped many organizations
become much more mobile with the use of the method, whereby point-of-receival/storage
analysis is possible. This technical note is the first of a two-part series that discusses the
critical issues behind material sampling. In particular, it addresses collecting the most
representative spectral measurements possible, enabling developing and deploying a robust
identification library.

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