Tag: chemical

Polarimetry Fundamentals

Polarimetry is a sensitive, non‐destructive technique for measuring the optical activity exhibited by inorganic and organic compounds. A compound is considered to be optically active if linearly polarised light is rotated when passing through it. The amount of optical rotation is determined by the molecular structure and concentration of chiral molecules in the substance. Each optically active substance has its own specific rotation.  The polarimetric method is a simple and accurate means for determination and investigation of structure in macro, semi‐micro and micro analysis of expensive and non‐duplicable samples. Polarimetry is employed in quality control, process control and research in the pharmaceutical, chemical, essential oil, flavour and food industries. Special applications are: Determination of product purity by measuring specific rotation and optical rotation of amino acids, amino sugars, analgesics, antibiotics, cocaine, codeine, dextrose, serums, steroids, tranquilizers and vitamins