SciMed has over 20 years direct experience of Supercritical CO2 processes.
Together with our partners, SciMed can offer a complete range of systems, often tailored to suit very specific and one-off design requirements, as well as simpler entry level solutions.
All the systems provided by SciMed are modular and can therefore be modified with ease, as and when requirements change.
SciMed has supplied numerous systems for all Supercritical CO2 applications including:
vreactions in Supercritical CO2
vSFE: Supercritical Extraction solutions for solids as well as counter column systems for continuous extraction of liquids
vparticle generation using CO2 as a solvent (RESS)
vparticle generation using CO2 as an anti-solvent (SAS, OR PCA).
A typical SFE ( Supercritical Fluid Extraction) system consists of the following components:
• CO2 pump – Ideal for high pressure, supercritical fluids, and pulseless flow applications.
• Co-solvent pump – Pumps a co-solvent as a percentage of the carbon dioxide flow rate up to its maximum flow rate and pressure rating. Adding a co-solvent like food grade ethanol allows one to extract polar compounds.
• Cooling heat exchanger – Cool and liquefy CO2 before it enters the pump for maximum efficiency.
• Flow meter – Located on the inlet of the carbon dioxide pump, the pump, for flow control, uses measured liquefied CO2 mass output from the flow meter.
• Heat exchanger – Located upstream from the vessel to ensure that the fluid is heated prior to entering the vessel.
• Extraction vessels – Caps with spring-loaded seal enhances safety, and lend to automation for efficient loading and unloading of large vessels. There can be up to two in a system.
• Automated BPR – Motor-driven and temperature-controlled to compensate for cooling during depressurization. A built-in pressure sensor provides closed loop feedback for control and pressure alarm monitoring.
• Collection vessels with manual BPR – The mixed fluid is introduced into the high pressure collection vessels, efficiently separated, and collected at the bottom of the vessels. There are three in a system, allowing for efficient collection of different extracts by varying pressure between collection vessels with the MBPRs.
• Recycler – Reclaims vented CO2 from extraction process. This system consists of storage vessel with level sensor for CO2 storage, level sensor module to display level, condensing heat exchanger, condensing cooling bath, and valves. The system also features a pressure relief valve that can be piped to vent to relieve pressure in case of over-pressurization or overfill conditions.
These rigs are available at various volumes. Some rigs can be designed to allow a combination of the above named applications, all on one rig.
SciMed’s Product Specialists can provide full customer support, including method development, contract research, service and application support.
Below are some example systems we have built:
Benchtop design to fit into a fume hood