Webinar for the Pharmaceutical Industry: latest developments in analytical and characterisation methods

Thursday 22nd April 2021 – Online

SciMed are once again holding their popular one-day seminar on techniques for the Pharmaceutical Industry, from research, formulation to manufacturing of solid doses and vaccines

This free to attend event includes a number of technical talks with technical experts who will provide in depth insights into a range of analytical and testing techniques relevant to the pharmaceutical industry

The program will include the following talks:

10:00 – Thermal Analysis and Calorimetry Applied to the Characterization of Pharmaceutical Materials, Formulations, and Drug Delivery Systems

11:00 – Scanning Electron Microscopy: looking closer at your formulations

12:00 –Product Showcase: a rapid insight (6minutes talk)  into multiple test methods and chemical processing solutions:

  • High Pressure Reactors and Hydrogenators
  • Refractometer and Polarimeters
  • Flame Photometer
  • Hand Held Raman and NIR for Raw Material ID
  • Supercritical Co2 processes for extraction, reaction and particle generation
  • Testing Powder Flowability with a Ring Shear Tester
  • USP 232/233 by ICP-OES and ICP-MS
  • UV/Vis – Specord 600  for dissolution monitoring
  • Traceable microwave digestion sample preparation

14:00 – X-ray powder solutions of pharmaceuticals for R&D and Quality control of purposes

15:00 -Recent advancements in X-ray CT for pharmaceutical applications

16:00 – Total organic carbon and nitrogen analysis in pharmaceutical compounds

Abstracts for the talks:

Thermal Analysis and Calorimetry Applied to the Characterization of Pharmaceutical Materials, Formulations, and Drug Delivery Systems:

In this webinar we will briefly introduce different thermal analysis techniques such as DSC, TGA and microcalorimetry and then focus on the Setaram range of instruments and how they can be used for analysis in the pharmaceutical arena. We will show with examples how thermal analysis can be used to  understand and elucidate pharmaceutical materials in terms of their crystallinity, purity, stability and compatibility.

Scanning Electron Microscopy: looking closer at your formulations   : SEM provides imaging and elemental analysis of features at the nanometre and micrometre scale and is a key tool in the Pharmaceutical industries. Typical routine applications include measurement of the distribution, size and shape of excipients and API’s; measurement of coating thickness; and detection of contaminant particles.  At the research level SEM provides examination of structural, physiochemical and surface features for crystal and particle engineering; observation of particle formation in the stabilisation of therapeutic agents for storage and distribution; the development of processes to improve the bioavailability of poorly soluble drugs and inhaled therapies; imaging the interaction between therapies and cells, development of novel antibacterial powders, and in many, many other novel applications. In this webinar we give an overview of the features and performance of benchtop SEM and provide an online demonstration of the analysis of pharmaceutical materials.


X-ray powder solutions of pharmaceuticals for R&D and Quality control of purposes: X-ray diffraction (XRD) is an very well established analytical method in drug discovery and production quality control. In this talk we will be exploring  a number of Pharma specific (and sometimes unique) solutions on offer from Rigaku. Ranging from very flexible Audit trail & electronic record/electronic signature (ER/ES) system that allow the user to easily toggle between GMP and non GMP modes, a unique combined XRD/DSC attachment allowing for both XRD and DSC analysis to be carried out simultaneously, a high throughput screening system for both reflection and transmission, variable temperature and Humidity solutions and much much more.

Recent advancements in X-ray CT for pharmaceutical applications: This presentation will briefly cover the basics of X-ray CT data collection and analysis. Then recent advancements in the technique, such as the application of deep-learning image segmentation, will be discussed. You will also see a number of application examples, including the investigation of cracks and aggregation inside tablets, analysis of tablet and drug particle coating thicknesses, and in-situ observation of the dissolving process.

Total organic carbon and nitrogen analysis in pharmaceutical compounds:

TOC is a parameter of importance in both the production and packaging of pharmaceuticals as the TOC content can be used as a reliable indicator of organic impurities. The determination of TOC in order to verify the quality and purity in water is therefore indispensable in many pharmaceutical applications. We will explore ultrapure water testing and cleaning validation, analysis of extractable organic components from packaging materials and the analysis of rinse-and-swab samples. In pharmaceutical vaccine production the starting, intermediate and end products all need to be controlled for the level of antigens. These antigens typically consist of proteins so the analytical quantification of total protein is necessary. There are several different assays in the pharmacopoeia regulations, such as UV/Vis assays (e.g., Lowry, Bradford, BCA assay) and two total nitrogen methods, including Kjeldahl. We will explore an automated alternative to these methods.

Interested and thinking of attending?

The seminar will be held online. Each talk will be run a an individual webinar with a separate invitation.


To attend please fill out the registration form by clicking the link below, choose the topics you want to attend and an online invitation will be sent for each one. There will be a short break between each talk to allow a quick refill of your mug!


If you wish to contact us directy about this webinar please CLICK HERE to send us an email or call 01614429963 and ask for Paul Vanden Branden