EASY-V 3440 Surface Area & Porosimetry Analyzer Advanced Surface Area and Pore Size Analysis Equipment. OVERVIEW | FEATURES | ABOUT | ADVANTAGES | ENQUIRE / CALL BACK Product Overview The EASY-V 3440, a product of CIQTEK, is a state-of-the-art Surface Area Analyzer designed for meticulous surface area and pore size measurements. Utilising the static volumetric method, this instrument has achieved multiple international certifications, marking its position at a global standard. The EASY-V 3440, with its advanced features, has been embraced by numerous universities and research institutions worldwide, making it a trusted name in material characterization. Features & Benefits Precision Guaranteed:…
MicroNIR PAT-L & PAT-Lx – Liquid Transmission Near Infrared Immersion Spectrometer for robust NIR analysis for liquids. Rugged, fast, and maintenance-free, the MicroNIR PAT-L transmission spectrometer is designed for real-time process monitoring in industrial and pharmaceutical process analytical technology (PAT) applications. ATEX and non-ATEX rated systems. https://youtu.be/-9JNFedekLY You can also visit the Viavi website for more product details by clicking on their logo below: Contact Us ENQUIRE CALL US LIVE CHAT * Live chat opening hours Mon – Fri 9:15 to 16:30 (UK Time.)
The PKS series models are extremely durable, large oil rotary vacuum pumps with very stable pumping characteristics. They are used in many applications, in areas ranging from the metal and automotive industries, to the chemical, pharmaceutical and food industries. Pumping Speed [96 to 420m3/h(1600 to 7000L/min)] You can also visit the ULVAC website for more product details by clicking on their logo below: Contact Us ENQUIRE CALL US LIVE CHAT * Live chat opening hours Mon – Fri 9:15 to 16:30 (UK Time)
PlasmaPURE Plus acids are manufactured with trace metal levels less than 10 ppt (0.01ppb). Commonly used in semiconductor, nuclear, clinical, pharmaceutical and geochemical analysis. Used for sample and standards preparation for ICP-AES, ICP-MS, Flame AA and Graphite Furnace AA spectroscopy. Supplied with a Certificate of Analysis containing lot number expiry date maximum specification for over 60 analytes Complete documentation for audit purposes Packaged in Class 10 clean room conditions – Supplied in preleached Teflon® bottles for optimum quality Available in sizes from 250 ml to 2 litres Acetic acid Ammonia solution Hydrochloric acid Hydrofluoric acid Nitric acid Sulfuric acid Hydrogen…
FlowViewTek offers a unique range of solutions enabling users to image liquid suspensions using any Scanning Electron Microscope (SEM) under full vacuum for a wide range of applications, including: Semiconductor and electronics Biological samples – including living cells Pharmaceuticals and cosmetics Energy and Batteries, for example lithium dendrites ISO&TR 13014, standard inspection for eight major physiochemical properties Traditional, SEM poses a number of obstacles to imaging liquid samples in their native state, such as:…
The CTX Texture Analyzer is an advanced model for compression and tension testing of materials. It allows quick, efficient testing for busy labs that need to improve productivity while maintaining quality. The CTX usability features allow for easy set-up and method development. It can be used in a wide range of markets – Food and Beverage, Cosmetics, Pharmaceuticals and Chemicals. Whether you are testing the consistency of pills and tablets, the peel ability of a yogurt lid, or the tensile strength of lipstick, the new CTX will meet the growing testing needs of the laboratory. TexturePro Software makes the CTX…
ApplicationDetermines the concentration of the optical active substance dissolved in an optically inactive liquid. The VariPol polarimeter is especially designed for pharmaceutical applications. The system is compact, includes peltier temperature control and is 21 CFR part 11 ready. Especially designed for pharmaceutical applications Peltier system for automatic temperature control 21 CFR part 11 ready Energy saving durable LED’s Control via touchscreen, PC, tablet or Smartphone Detailed specification for the Varipol are listed below Measurement scales ° Optical rotation, ° Specific rotation, °Z International Sugar Scale, % Concentration (g/mL, g/100mL, g/L), further scales freely definable Measuring range ± 89.9° Resolution 0.005°…
ApplicationContinuous density measurement of liquids. Suitability cosmetics food and beverage medicines paints and lacquers petroleum Markets brewing chemical cosmetics food and beverage lubricants neutraceutical petrochemical pharmaceutical Specification Integrated reference oscillator High-precision temperature measurement Automatic detection of gas bubbles High precision and reproducibility of 0.0005 g/cm³ Touch screen interface Optional moisture and air pressure sensor You can also visit the Schmidt & Haensch website for more product details by clicking on their logo below: Contact Us ENQUIRE CALL US LIVE CHAT * Live chat opening hours Mon – Fri 9:15 to 16:30 (UK Time)
Application Determines the density of liquids. Suitability cosmetics food and beverage medicines paints and lacquers petroleum Markets brewing chemical cosmetics food and beverage lubricants neutraceutical petrochemical pharmaceutical Specification Integrated reference oscillator High-precision temperature measurement Automatic detection of gas bubbles High precision and reproducibility of 0.0001 g/cm³ Touch screen interface Optional moisture and air pressure sensor For more details on Schmidt & Haensch density meters, please visit www.schmidt-haensch.com You can also visit the Schmidt & Haensch website for more product details by clicking on their logo below: Contact Us ENQUIRE CALL US LIVE CHAT * Live chat opening hours Mon –…
Dust Explosions can occur in many industries where powdered materials are handled. These include Pharmaceuticals, Fine Chemicals Food, Metals, Paper, Plastics, Rubber, and Textiles. The consequences of which can be catastrophic. SciMed through our partners are able to offer a full range of dust explosivity characterisation tests including: Minimum Ignition Energy (MIE) Minimum Ignition Temperature (MIT) Minimum Explosible Concentration (MEC) Explosion Severity (Kst, Pmax and dP/dtmax) Limiting Oxygen Concentration (LOC) Layer Ignition Test (LIT) Powder Resistivity Charge Relaxation Drying Tests Contact Us ENQUIRE CALL US LIVE CHAT * Live chat opening hours Mon – Fri 9:15 to 16:30 (UK Time)
Flexi-Hyco is a cutting-edge solution offered by Setaram Solutions that is designed to provide exceptional flexibility and control for high-pressure hydrogenation reactions. This innovative system combines the latest advancements in reactor technology with sophisticated control software to offer users an unparalleled level of precision and reliability. The Flexi-Hyco features a modular design that can be easily customized to suit a wide range of process requirements. The system includes a high-pressure reactor vessel, which is capable of accommodating pressures up to 200 bar, and a variety of optional accessories such as stirrers, pressure relief valves, and temperature sensors. One of the…
The NANO 3DX is an X-ray microscope (XRM) wich offer 3D computed tomography (CT) images with high contrast and at high resolution. This is accomplished by using a high powered rotating anode X-ray source and a high-resolution CCD detector. The rotating anode provides for fast data acquisition and the ability to switch anode materials easily to optimize contrast for specific sample types. High-resolution, high-contrast X-ray microscopeThe new nano3DX allows you see into many types of samples, including those that have low absorption contrast, for example CFRP, or denser materials like ceramic composites. The nano3DX allows you to achieve this by…
Description VIDEO Why Polarised optics? Application Description Second-generation Polarised Optics EDXRF from Rigaku.This New Generation instrument performs Quantitative and Qualitative Elemental Analysis What are the main features of the Rigaku NEX CGII? NEX CG II, performs elemental analysis of major, minor and trace elements from light elements – Na to heavy U. Measurements can be made of metals, glass and other solid matrices, powders of soils, geological matrices, polymers, pharmaceuticals and other powders, liquids, pastes, waste materials, thin films and coatings and any material that can be presented to the instrument in pre-defined cups or discs or any free form…
A single analyser for liquid, gaseous, solid and LPG samples The new multi EA® 5100 provides an all-round solution for the determination of carbon, nitrogen, sulphur and chlorine, but this is only a small part of what it can do. TOC, EOX or AOX/TOX analyses are further areas easily covered and its supremely flexibility means it can handle solids, liquids, pastes and gases. The new EA 5100 has a whole host of new improvements over the very successful and popular EA 5000. Here are some of the new developments Unique double furnace technology is now standard to ensure optimum results…
The multi EA® 5000 is extremely versatile: The determination of carbon, nitrogen, sulfur and chlorine is only a small part of what it can do. TOC, EOX or AOX/TOX analyses are further areas easily covered by the multi EA® 5000. This makes it a universal talent to be used in various fields. • Application diversity – one analyzer for solid, paste-like, fluid, gaseous and LPG samples • C, N, S and Cl determination in one instrument • Multi-matrix sampler, for fully-automated determination of solid and fluid samples in vertical or horizontal furnace configuration • • Extended measuring range with low…
The Multi N/C® range of TOC and TNb analyzers from Analytik Jena deliver robust, high performance results on an easy to use, low maintenance platform. Technology Highlights• Industry leading, high performance TOC for all applications.• No kits required for difficult high saline samples making the system easy to use.• Direct injection variable volume autosampler injects only the amount of sample required. Inject small volumes for concentrated samples or complex matrices or large volumes for enhanced sensitivity.• 10 year NDIR detector warranty• Sensitivity down to 2ppb, upper range of 30,000ppm without dilution.• Automatic sample preparation, sparging and acidification• Dedicated UK service…
Based on first principle of photo-sedimentation, the Brookhaven Instrument disc centrifuge instruments are the only optical disc centrifuge that measures particle size without calibration. The DCP has a traditional light source and the XDC use X-rays. These instruments measure the size of particles according to the time the particle takes to sediment in the detector according to Stokes Law. High resolution measurements are typically obtained in 5 to 30 minutes. Modelling software is included to predict optimal experimental conditions like disc speed and run time. The high resolution instrument can resolve peaks as close as a 13% size differential and…
The Ring Shear Tester RST-XS.s is compact and bench-mounted. It is designed for applications with powders of up to particle size 1.5 mm. This RST is particularly well-suited for small sample volumes. The RST-XS is an easy-to-operate, computer-controlled tester for the precise determination of the flow properties of fine-grained powders and bulk solids. It is appropriate for those industries and research institutions which deal with either fine-grained materials or have only limited amounts of powders for testing (e.g. pharmaceutical, food, chemical industries and others). The tester measures the flowability and other physical quantities like the internal friction of a powder,…
The MicroNIR Onsite from VIAVI (ex JDSU) is the world’s smallest NIR spectrometer. The ‘fit for purpose’ design allows the user to apply NIR in a way never seen before. The MicroNIR family of spectrometers is the next generation of ultra-compact near-infrared spectrometer sensors and analysers, solving customer needs across multiple industries. The pharmaceutical, agriculture and chemical industries have deployed the MicroNIR spectrometer for real-time, non-intrusive chemical and physical analysis of materials and monitoring of processes. This has resulted in improved quality control, reduced costs and faster decision-making. The MicroNIR spectrometer’s small form factor, its cost-effectiveness, exceptional performance and ease…
The MicroNIR PAT is an ultra-compact, near-infrared (NIR) wireless spectrometer covering 950 – 1650 nm for on-line process monitoring applications in the pharmaceutical, food, and chemical industries. It is suitable for batch processes. The MicroNIR PAT also allows continuous manufacturing processes that use multiple NIR sensors across an entire process flow. Pharma applications includes monitoring blend uniformity, drying conditions, and API concentrations in blenders, fluid bed dryers, and tableting. The MicroNIR PAT is available as a wired or wireless device. The MicroNIR PAT WIFI: • non-destructive, non-invasive, and real-time near-infrared analysis• user-selectable WiFi or Ethernet for system control and data…
Available in both a ball bearing and air bearing models, the Thermo Haake Viscotester iQ rheometer is ideal for QC measurements. With a wide range of accessories and temperature control module options, the VTiQ is the smallest commercially available rheometer on the market. The VTiQ can be used stand-alone or with software to allow for both simple and more complex rheological characterisation of liquids, semi-solids and pastes. Industrial QC applications include: * Food * Polymers * Pharmaceuticals * Building materials * Cosmetics * Paints and inks Photo Gallery Video Gallery Introducing the HAAKE Viscotester iQ Rheometer HAAKE Viscotester- Prevent measuring…
The Thermo Haake Mars rheometer can be used for advanced R&D and quality control. With wide-ranging applications and accessories, the Mars rheometer can be used for complex material characterisation. The modular system allows for the Thermo RheoScope (for micro-viewing) and Thermo Rheonaut (for FTIR analysis) to be integrated into rheological measurements. Applications of the Mars rheometer include: * Food* Paints and inks* Polymers* Pharmaceuticals* Cosmetics* Petrochemicals* Building materials Photo Gallery Video Gallery Performing UV curing measurments on the Thermo Scientific HAAKE MARS 40/60 Rheometer How to perform a measurement with the RheoRaman System Thermo Scientific HAAKE MARS Rheometer Platform The…
The Mars iQ rheometers are available with either a ball bearing or air bearing configuration, that can be used in conjunction with a wide range of accessories and temperature control modules. Ideal for testing liquids, slurries, polymers, semi-solids and suspensions, the Mars iQ rheometers can be used for research and quality control purposes. With a broad range of applications in both industry and education, the Mars iQ rheometers deliver fast, reliable results. Applications include: * Food* Paints and inks* Polymers* Cosmetics* Pharmaceuticals* Petrochemicals* DSR testing of asphalt and bitumen* Building materials Photo Gallery Video Gallery HAAKE MARS iQ Rheometer Performing…
Flame Photometry is the technique of choice for the measurement of sodium, potassium and calcium in all sample types for: • mineral extraction• oil industry• paper industry• pharmaceuticals• soil analysis• utilities• food and beverage• chemical manufacture• fertilisers Sherwood Scientific’s Model 410 Industrial Flame Photometer with digital output (for printer or PC connection), also offers sodium linearization capability to allow higher concentrations of Sodium (<40 ppm) to be directly measured using a single point calibration. This facility can be switched on or off according to the operator’s preference or protocol for sodium determinations. The Model 410 also has sodium, potassium and…
Sherwood Scientific have developed and manufactured a range of two general purpose Fluid Bed Dryers (FBDs): one analogue and one with digital controls of airspeed, temperature and time. In addition, Sherwood Scientific have also developed a programmable FDB where drying programmes can be created and stored on computers. BenefitsThe laboratory fluid bed dryer offers significant advantages over conventional drying techniques: • The high rates of heat and mass transfer ensure much faster and more homogeneous drying than other methods such as oven and vacuum drying.• Drying times range from a few seconds to minutes. Complete drying is usually achieved in…
The Sherwood Model 926 Chloride Analyser is used for the determination of Chloride Ions (Cl-) in both human and animal food products, agriculture, cement, gypsum and the pharmaceutical and water industries. Sample preparation is minimal for most products with running costs of approximately £0.20/test. The Sherwood Model 926S is used in clinical laboratories, generally for sweat test analysis on infants. It is calibrated at 100mmol/L. Sample size for this application is user selectable at 20ul or 100ul. You can also visit the Sherwood website for more product details by clicking on their logo below: Contact Us ENQUIRE CALL US LIVE…
Thermal analysis is widely used in the pharmaceutical industry to measure properties such as polymorphism, excipient compatibility, purity, melting points and humidity studies.
The crystal systems of pharmaceuticals and foods may change due to factors such as temperature and humidity. The climate of Japan in particular exhibits extreme changes in temperature and humidity, with hot and humid summers, and dry, low-temperature winters, and these are poor conditions as an environment for synthesizing pharmaceuticals or storing foods. Therefore, there is a need to conduct measurement beforehand under various atmospheric conditions, and determine what sort of changes these materials undergo in the actual environment. Thus we evaluated thermal changes and changes in the crystal structure of pharmaceuticals by simultaneously measuring X-ray diffraction (XRD) and differential…
In the tableting process for pharmaceuticals, it sometimes happens that the active pharmaceutical ingredient reacts with materials used as excipients, such as sugar or starch, and dehydration reactions, polymorph transitions and other processes may occur due to the pressure during tableting. In recent years, a need has arisen to check, in the shortest possible time, whether or not the active pharmaceutical ingredient maintains its original crystal system, and whether or not there are polymorph impurities. Furthermore, this must be done in the tableting process, while maintaining the tablet form. Therefore, we used a powder X-ray diffractometer to non-destructively measure the…
Bulk samples such as metal blocks, ceramic sintered bodies, or pharmaceutical tablets are aggregates of microcrystals that can be measured by powder X-ray diffraction. In conventional powder diffraction measurements, samples need to be filled into a sample holder the size of a typical coin and placed in the center of the diffractometer. Hence, to perform measurements of bulk samples, it has been necessary to cut or pulverize samples according to the sample holder, or to use an attachment with an electrically driven adjustment axis in the thickness direction of the sample. With Rigaku’s bulk sample holder, thick bulk samples can…
Quantification of a trace amount of polymorphic impurities is critical especially in the quality control of Active Pharmaceutical Ingredients (APIs). Conventional quantitative analysis by X-ray diffraction (XRD) requires calibration curve preparation, reference intensity ratio (RIR) or crystal structure (Crystallographic Information File, CIF). However, the materials of APIs are often missing from the database. Therefore, their quantification is not straightforward. Rigaku have developed a novel quantitative analysis method called “Direct Derivation (DD)” that requires only XRD data and chemical formula(1)- (3). Here, quantitative analysis of trace amounts of the hydrate phase of API is performed using the DD method and the…
Many active pharmaceutical ingredients have multiple crystal forms, and it is known that solubility and bioavailability vary depending on the crystal form. In the drug manufacturing process, active ingredients may sometimes undergo a crystalline phase transition to another crystal form, due to factors such as heat, light, humidity or pressure, and there is a need to check what crystal form the ingredient is in, in its final product state. With optical systems employing the Bragg-Brentano focusing method, of the type generally used with powder X-ray diffractometry, measurement of the powdered sample is done with a reflection arrangement, but if a…
Urea is an organic compound that plays an important role in biological metabolism processes. Besides its physiological properties, synthetically synthesized urea has become a very meaningful compound in the clinical, pharmaceutical, and chemical industries. It is a starting material for the synthesis of a large number of chemicals including hydrazine and melamine that are further used for the production of resins eventually used as building materials. In agriculture, urea is a preferred compound to be used as fertilizer because of its high nitrogen content. Another application with constantly rising importance is it use as an active ingredient in exhaust gas…
Sunflower oil is a vegetable oil that is commonly used as main component or supplement in food, such as frying oil, salad dressing, baby food, margarine, or mayonnaise. Furthermore, it is used as an additive in cosmetics, biodiesel, varnish, textiles, and pharmaceuticals. Sunflower oil is among the most widely produced vegetable oils and is obtained from the seeds of the sunflower plant. The production includes the initial oil extraction by pressing (cold or hot) and refining processes such as solvent extraction, degumming, bleaching, and dewaxing. Refining sunflower oil increases its heat stability for frying and cooking purposes but is known…
Chapter and ICH Q3D specify maximum limits for the amount of elemental impurities permitted in drug products, drug substances, active ingredients and excipients. These impurities may be present naturally, derived from the production catalysts or introduced inadvertently through the manufacturing process, or they could be environmental contaminants in the pharmaceutical raw materials. When elemental impurities have the potential to be present, compliance to the specified levels is a requirement. Here we present a simple and effective method for routine preparation and analysis of pharmaceutical material according to ICH and USP 232 and 233.
The USP represents the general method for TOC testing in pharmaceutical applications and provides guidance on how to qualify the analytical technique for use as well as guidance on how to interpret instrument results for use as a limit test. A wider concentration range has to be covered by the TOC method applied and an SST test at 8 ppm must be passed.
In pharmaceutical vaccine production, starting, intermediate and end products need to be controlled for the level of antigens. They are tested for the quantity of attenuated or devitalized viruses or bacteria. Since these antigens typically consist of proteins, the analytical quantification of total protein is a method of choice. Pharmacopoeia regulations list a number of relevant methods, among them are several UV/Vis assays (e.g. Lowry, Bradford, BCA assay) and two total nitrogen methods, which is the Kjeldahl and the catalytic combustion method. This application note focuses on the catalytic combustion method which is described in Pharm. Eur. Monograph 2.5.33, Method…
For many years now, the pharmaceutical industry has adopted Near Infrared Spectroscopy (NIRS) for various applications, particularly raw material identification and qualification. When the US FDA released its PAT Framework document in 2004, many of the larger innovator companies dedicated much time and effort into the development of NIRS for real time monitoring and control applications in solid dose manufacturing. One of the key processes targeted was Fluid Bed Drying (FBD) because of the static nature of the process and its criticality to downstream manufacturing operations. Many of these companies also used dynamic blenders for their blending operations, however, during…
For many years, pharmaceutical and related industries have used near-infrared spectroscopy (NIRS) as a means to identify raw materials as they are received by a manufacturing facility. The NIRS technique is highly specific for many of the organic compounds used in the formulation of tablets, capsules, crèmes, and suspensions. The development of portable and smaller instrumentation has helped many organizations become much more mobile with the use of the method, whereby point-of-receival/storage analysis is possible. This technical note is the first of a two-part series that discusses the critical issues behind material sampling. In particular, it addresses collecting the most…
Technological advances in analytical instrumentation and computing systems have allowed many industries to better monitor and control business critical processes. This has enabled proactive, not reactive approaches to real-time quality assurance and product release. Until the advent of QbD and subsequent PAT initiatives, pharmaceutical and related industries were not fully equipped with the right guidance and supporting architecture to gain the benefits of modern, state-of-the-art quality control and assurance systems.
NIR spectroscopy is a desirable methodology due to its unique ability to measure a wide range of different material types such as powders, liquids, solids, and slurries—often with little or no sample preparation. Users can measure these materials in their current states, saving analysis time and increasing sample analysis throughput. However, when developing a method for NIR spectroscopy, care should be taken to ensure that the sample presentation is both repeatable from user to user and is reproducible over time.
Polarimetry is a sensitive, non‐destructive technique for measuring the optical activity exhibited by inorganic and organic compounds. A compound is considered to be optically active if linearly polarised light is rotated when passing through it. The amount of optical rotation is determined by the molecular structure and concentration of chiral molecules in the substance. Each optically active substance has its own specific rotation. The polarimetric method is a simple and accurate means for determination and investigation of structure in macro, semi‐micro and micro analysis of expensive and non‐duplicable samples. Polarimetry is employed in quality control, process control and research in the…
Determines low concentrations of water in a wide range of liquid, gas and powder samples. Used for assessing water content in petroleum and petrochemical products including oils, gasolines, solvents, and fluids as well as other products such as pharmaceuticals and cosmetics.
ASTM Colour: For the visual determination of the colour of a wide variety of petroleum products, such as lubricating oils, heating oils, diesel fuel oils, and petroleum waxes. Saybolt Colour: Determines the colour of refined oils such as undyed motor and aviation gasoline, jet propulsion fuels, naphthas and kerosine, and, in addition, petroleum waxes and pharmaceutical white oils.
Raw material identification or verification (of the packaging label) is a common quality-control practice. In the pharmaceutical industry, the increasing global footprint of the supply chain and public health concerns1 resulting from contaminated materials (or mislabeling) have driven many regulatory bodies to require inspection of every barrel in every shipment of materials used in the manufacture of pharmaceutical drugs. Handheld analytical instruments are becoming more common for rapid and non-destructive testing of incoming raw materials directly in warehouses, reducing the cost and time needed for taking samples to the laboratory and quarantining incoming shipments until lab testing is complete.